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Principal Investigator: Dr. Sam Makhoul
Study ID Name: D926XC00001, Tropion Breast-03
Sponsor: AstraZeneca
Protocol Title: A Study of Dato-DXd With or Without Durvalumab Versus Investigator’s Choice of Therapy in Patients With Stage I-III Triple-negative Breast Cancer Without Pathological Complete Response Following Neoadjuvant Therapy
Clinicaltrials.gov Number: NCT05629585
Principal Investigator: Dr. Sam Makhoul
Study ID Name: D8534C00001, Serena-6
Sponsor: AstraZeneca
Protocol Title: A Phase III, Double-blind, Randomised Study to Assess Switching to AZD9833 + CDK4/6 Inhibitor vs Continuing AI + CDK4/6 Inhibitor in HR+/HER2- MBC Patients with ctDNA Detectable ESR1 Mutation Without Disease Progression During 1L Treatment
Clinicaltrials.gov Number: NCT04964934
Principal Investigator: Dr. Sam Makhoul
Study ID Name: SGNTUC-028, HER2Climb-05
Sponsor: Seagen
Protocol Title: A randomized, double-blind, phase 3 study of tucatinib or placebo in combination with trastuzumab and pertuzumab as maintenance therapy for metastatic HER2+ breast cancer
Clinicaltrials.gov Number: NCT05132582